No mater which media you use do not breath the dust. Some the finer stuff takes a bit longer to get trough the paint, and also the rust, but it will not eat way on as much good stuff as quick.
How much rust and stuff is on it. It may be better to do something like rust remover, that does not harm the good metal. Some of the abrasives if they hit a soft spot will dig in, I have done some with standard Alum ox, all the way up to the black diamond stuff and now do a lot a strip with a good stripper, cleaned off with a pressure washer, then either electrolysis, Molasses mix, or smaller pieces put into an evaporust soak. That way I am not taking anything that is good down any.